Today, i chose to write on depression because it’s the commonest mental health problem and a major contributor to the overall global burden of disease.
Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest and negatively affects how you feel, the way you think and how you act. It results from a complex interaction of social and environmental factors.
Most people with depressive disorder usually have masked symptoms which can include;
- loss of sexual desire
- Suicidal thoughts
- Weight loss
Drug treatment for depression includes the use of Anti-depressant drugs, which includes the following classes of drugs.
- Selective serotonin reuptake inhibitors (SSRIs): This drugs blocks the reuptake of serotonin into neurons. Examples of drugs in this class are Citalopram, Fluoxetine, Sertraline.
- Serotonin/norepinephrine reuptake inhibitors (SNRIs); This drugs blocks the reuptake of serotonin and norepinephrine into neurons.
- Tricyclic antidepressants (TCAs): They block the reuptake of serotonin and norepinephrine. Examples of drugs in this class are; Amitriptyline, Desipramine, Imipramine, Nortriptyline.
- Monoamine oxidase inhibitors (MAOIs): This class of drugs inhibit Monoamine oxidase, thus sparing the enzymatic break down of mono amines. Examples of drugs in this class are; selegiline, isocarboxazid, phenelzine.
- Atypical antidepressants; Atypical antidepressants are drugs that don’t belong to the above classes. Examples of drugs in this class are; Bupropion, Mirtazapine.
Possible side effects of Anti-depressants may include, among others:
• Nausea, vomiting or diarrhea
• Dry mouth
• Sexual problems (erectile dysfunction)
Cognitive behavioral therapy (CBT) is a type of psychotherapy based on the idea that negative feelings are the result of current distorted thoughts. This form of therapy is based on the idea that unhealthy behaviors can be changed. CBT is quite effective alongside pharmacological therapy for depressed people.